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How is Schistosomiasis diagnosed? Anybody who has been in areas of the world where schistosomiasis is endemic or known to exist, has been in contact with fresh water and has some of the signs and symptoms mentioned above, they should tell their doctor or contact a health clinic. In Europe, the USA, Canada and Japan the GP (general practitioner, primary care physician) will interview and examine the patient and refer him/her to an infectious disease or tropical medicine specialist. The National Health Service (NHS), UK, advises anybody who has been to an area where Schistosomiasis is known to occur, and was in contact with contaminated fresh water, to have a check-up three months after the last possible exposure - even if they have no signs or symptoms. The patient will be asked by the doctor where they have travelled, how long they were there, and whether there was any contact with contaminated water. 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Eggs can be detected in the urine in infections with S. The worm takes about 40 days to mature; so it may take three months after exposure to contaminated water before the blood sample can provide any reliable results. If the patient has intestinal symptoms a biopsy of the rectum may be ordered. The doctor may also order a biopsy if he/she suspects infection, but urine and blood samples are negative. What are the treatment options for Schistosomiasis? Praziquantel - a medication which is given as a short course generally clears up the infection. Even patients in advanced stages will be effectively treated. 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